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Personal Information

Name Hirokawa Nobutaka Hirokawa, Nobutaka
Section Section II, Seventh Subsection
Date of Election 2004/12/13
Speciality Molecular Cell Biology
Selected Bibliography
    1. Hirokawa, N. Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method. Journal of Cell Biology 94(1): 129-142, 1982.
    2. Hirokawa, N., K.K. Pfister, H. Yorifuji, M.C. Wagner, S.T. Brady, and G.S. Bloom. Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration.Cell 56(5): 867-878, 1989
    3. Okada, Y., H. Yamazaki, Y. Sekine-Aizawa, and N. Hirokawa. The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81(5): 769-780, 1995.
    4. Hirokawa, N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279(5350): 519-526, 1998.
    5. Nonaka, S., Y. Tanaka, Y. Okada, S. Takeda, A. Harada, Y. Kanai, M. Kido, and N. Hirokawa. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95(6): 829-837, 1998.
    6. Okada, Y., and N. Hirokawa. A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A. Science 283: 1152-1157, 1999.
    7. Setou, M., T. Nakagawa, D.H. Seog, and N. Hirokawa. Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288(5472): 1796-1802, 2000.
    8. Kikkawa, M., E.P. Sablin, Y. Okada, H. Yajima, R.J. Fletterick, and N. Hirokawa. Switch-based mechanism of kinesin motors. Nature 411(6836): 439-445, 2001.
    9. Homma, N., Y. Takei, Y. Tanaka, T. Nakata, S. Terada, M. Kikkawa, Y. Noda, and N. Hirokawa. Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell 114: 229-239, 2003.
    10. Nitta, R., M. Kikkawa, Y. Okada, and N. Hirokawa. KIF1A alternately uses two loops to bind microtubules. Science 305: 678-683, 2004.
    11. Hirokawa, N. and R. Takemura. Molecular motors and mechanisms of directional transport in neurons. Nature Reviews Neuroscience 6: 201-214, 2005.
    12. Hirokawa, N., Y. Tanaka, Y. Okada and S. Takeda. Nodal flow and the generation of left-right asymmetry. (Review Article) Cell 125(1): 33-45, 2006.
    13. Midorikawa, R., Y. Takei, and N. Hirokawa. KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity. Cell 125: 371-383, 2006

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