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Proceedings of the Japan Academy, Ser. B, Physical and Biological Sciences

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The Proceedings of the Japan Academy, Series B was founded in 1912 as the Proceedings of the Imperial Academy by the then Imperial Academy of Japan (now the Japan Academy). The Journal was split to the Proceedings of the Japan Academy, Series A and Series B in 1977. PJA Series B publishes reviews and original articles in broad fields of natural sciences, such as chemistry, physics, astronomy, earth sciences, biology, engineering, agricultural sciences and medical sciences. All manuscripts are evaluated at least by two reviewers. Ten issues are published per year. The entire content is now freely available online through J-STAGE.

Vol. 90 No. 10 (2014)


Reviews
Stereochemical studies on pheromonal communications
Kenji MORI
Proc. Jpn. Acad., Ser. B, Vol. 90, 373-388 (2014) [abstract] [PDF]
The molecular basis of myeloid malignancies
Toshio KITAMURA, Daichi INOUE, Naoko OKOCHI-WATANABE, Naoko KATO, Yukiko KOMENO, Yang LU, Yutaka ENOMOTO, Noriko DOKI, Tomoyuki UCHIDA, Yuki KAGIYAMA, Katsuhiro TOGAMI, Kimihito C. KAWABATA, Reina NAGASE, Sayuri HORIKAWA, Yasutaka HAYASHI, Makoto SAIKA, Tomofusa FUKUYAMA, Kumi IZAWA, Toshihiko OKI, Fumio NAKAHARA and Jiro KITAURA
Proc. Jpn. Acad., Ser. B, Vol. 90, 389-404 (2014) [abstract] [PDF]
Genomic study of ossification of the posterior longitudinal ligament of the spine
Shiro IKEGAWA
Proc. Jpn. Acad., Ser. B, Vol. 90, 405-412 (2014) [abstract] [PDF]
Original Articles
Feasibility studies towards future self-sufficient supply of the 99Mo-99mTc isotopes with Japanese accelerators
Kozi NAKAI, Naruto TAKAHASHI, Jun HATAZAWA, Atsushi SHINOHARA, Yoshihiko HAYASHI, Hayato IKEDA, Yasukazu KANAI, Tadashi WATABE, Mitsuhiro FUKUDA and Kichiji HATANAKA
Proc. Jpn. Acad., Ser. B, Vol. 90, 413-421 (2014) [abstract] [PDF]
Toward the detection of gravitational waves under non-Gaussian noises I. Locally optimal statistic
Jun'ichi YOKOYAMA
Proc. Jpn. Acad., Ser. B, Vol. 90, 422-432 (2014) [abstract] [PDF]
Cover Illustration
A pheromone can attract beetles

  A sex pheromone is produced by either male or female of an organism, and attracts the same organism of opposite sex. Since 1959 when the discovery of the female-produced sex pheromone of the silkworm moth was reported, many pheromones were isolated and identified so as to clarify the chemical communication systems among organisms, hoping to utilize them as environmentally benign tools for pest managements.
  The cover picture illustrates the stereostructure of serricornin, the female-produced sex pheromone of the cigarette beetle. It possesses three asymmetric carbon atoms, and therefore eight stereoisomers are possible for it. Enantioselective synthesis of the stereoisomers of serricornin revealed its (4S,6S,7S)-isomer to be the naturally occurring and bioactive isomer. Mori's studies on pheromones including serricornin by means of enantioselective synthesis contributed very much to clarify the stereochemistry of pheromone perception as summarized in his review in the present issue on pp. 373-388.
  Serricornin is actually employed in pest management. Male cigarette beetles (left) can be attracted by a pheromone-baited trap (center) to be caught on a sticky material inside of the trap (right). The traps are now used in many food factories, flour mills and cigarette factories.
  (4S,6S,7S)-Serricornin exists as an equilibrium mixture of the acyclic hydroxyl ketone form (left) and the cyclic hemiacetal form (right). Which is the bioactive form to be recognized by the pheromone receptor of the cigarette beetle? That is an open question.

Teruhiko Beppu
Member of the Japan Academy

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